{"product_id":"glucosamine-for-dogs","title":"Glucosamine for Dogs","description":"\u003ch1\u003eDogs Joints and cartilage – what is this all about?\u003c\/h1\u003e\n\u003cp\u003eA joint is the point where two bones move against each other. To ensure smooth, friction-free movement – no sandpaper – the joint surfaces are covered with \u003cem\u003ecartilage tissue\u003c\/em\u003e. The role of cartilage is to enable movement, absorb load, and provide a slippery surface for the bone surfaces. Think of cartilage as a \u003cem\u003esliding surface and shock absorber\u003c\/em\u003e that is involved in everyday movements: walking, trotting, jumping, and working.\u003c\/p\u003e\n\u003cp\u003eCartilage tissue is living tissue that is constantly renewed and remodelled as part of the body's normal metabolism. It receives its nutrients from the surrounding synovial fluid and tissue metabolism. Movement is important for joints, and the metabolism of cartilage tissue is then active.\u003c\/p\u003e\n\u003ch2\u003eGlucosamine – part of joint structure\u003c\/h2\u003e\n\u003cp\u003eGlucosamine naturally occurs in the body as part of cartilage tissue, ligaments, tendons, synovial fluid, and the intervertebral discs of the spine. It belongs to the compounds of connective and supportive tissues and is involved in the normal metabolism of cartilage tissue.\u003c\/p\u003e\n\u003cp\u003eIn feeding, glucosamine is used as a complementary nutrient as part of a balanced diet, particularly for \u003cem\u003eactive\u003c\/em\u003e and mobile dogs whose daily movement involves repetitive loading.\u003c\/p\u003e\n\u003cp\u003eIn studies, glucosamine has most often been examined together with chondroitin. Cartilage tissue is made up of several structural compounds that together give it its flexible and durable structure. Glucosamine is part of this whole. As an animal ages and its life stage changes, \u003cmeta charset=\"utf-8\"\u003ejoint structures also renew more slowly than in a young animal – and this is worth considering in feeding as well.\u003c\/p\u003e\n\u003ch2\u003eCdG's glucosamine – a plant-based and modern alternative\u003c\/h2\u003e\n\u003cp\u003eThe glucosamine used by CdG is 100% plant-based and vegan, and it is manufactured using a patented fermentation technique. Unlike traditional crustacean-derived glucosamine, this alternative requires no crustaceans and no heavy chemical processing.\u003c\/p\u003e\n\u003cp\u003eThe production of plant-based glucosamine generates only about 2% of the wastewater produced in the manufacture of crustacean-derived glucosamine. The end result is an environmentally friendly and responsible raw material – without crustaceans and without unnecessary environmental impact.\u003c\/p\u003e\n\u003ch2\u003eDosage:\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eMeasures:\u003c\/p\u003e\n\u003cp\u003e1 tbsp = 10 g (8 300 mg glucosamine)\u003c\/p\u003e\n\u003cp\u003e1 tsp = 3,3 g (2 700 mg glucosamine)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDogs:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eunder 3 kg: 1\/5 tsp \/ day (540 mg)\u003c\/p\u003e\n\u003cp\u003e3–5 kg: 1\/4 tsp \/ day (675 mg)\u003c\/p\u003e\n\u003cp\u003e5–15 kg: 1\/3 tsp \/ day (900 mg)\u003c\/p\u003e\n\u003cp\u003e15–30 kg: 1\/2 tsp \/ day (1 350 mg)\u003c\/p\u003e\n\u003cp\u003e30–45 kg: 2\/3 tsp \/ day (1 800 mg)\u003c\/p\u003e\n\u003cp\u003e45–60 kg: 2\/3–1 tsp \/ day (1 800–2 700 mg)\u003c\/p\u003e\n\u003cp\u003eFor continuous use, the dose can be halved after 6–8 weeks as part of normal feeding adjustment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eComposition:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eGlucosamine hydrochloride\u003cbr\u003e– of which glucosamine 83%\u003cbr\u003e– 830 000 mg glucosamine \/ kg\u003c\/p\u003e\n\u003cp\u003eNote:\u003cbr\u003eNot suitable for those with corn allergy. Glucosamine is corn-derived.\u003c\/p\u003e\n\u003ch2\u003eResearch background – glucosamine in dogs\u003c\/h2\u003e\n\u003cp\u003eGlucosamine has been studied in both dogs, particularly in the research literature related to joint structures. A large proportion of published studies have examined combinations of glucosamine and chondroitin sulphate, often in veterinary or experimental settings.\u003c\/p\u003e\n\u003cp\u003eIn equine studies, the use of glucosamine-containing combinations has been examined in experimental models and clinical evaluations related to joint structures. In dogs, glucosamine has been studied particularly as part of combination products.\u003c\/p\u003e\n\u003cp\u003eCurrent research evidence supports the understanding that glucosamine is a natural part of the composition of joint structures, and its use in feeding is based on this structural role as part of a balanced complementary feeding regime.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-end=\"567\" data-start=\"370\"\u003e\n\u003cp data-end=\"567\" data-start=\"373\"\u003e\u003cstrong data-end=\"397\" data-start=\"373\"\u003eHanson RR et al. (2001)\u003c\/strong\u003e – oral glucosamine HCl + chondroitin sulphate (Cosequin) vs. placebo; clinical setting (navicular syndrome).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"795\" data-start=\"568\"\u003e\n\u003cp data-end=\"795\" data-start=\"571\"\u003e\u003cstrong data-end=\"596\" data-start=\"571\"\u003eMoreira JJ et al. (2019)\u003c\/strong\u003e – oral glucosamine + chondroitin sulphate; synovial fluid biomarkers were measured in horses (osteoarthritis-related joint setting).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"964\" data-start=\"796\"\u003e\n\u003cp data-end=\"964\" data-start=\"799\"\u003e\u003cstrong data-end=\"824\" data-start=\"799\"\u003eYamada ALM et al. (2022)\u003c\/strong\u003e – glucosamine + chondroitin sulphate; experimental setting in horses (experimentally induced OA).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"1170\" data-start=\"965\"\u003e\n\u003cp data-end=\"1170\" data-start=\"968\"\u003e\u003cstrong data-end=\"993\" data-start=\"968\"\u003eMeulyzer M et al. (2009)\u003c\/strong\u003e – pharmacokinetic \/ synovial fluid concentration study: glucosamine levels in the equine joint (normal vs. inflamed joint).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"1393\" data-start=\"1171\"\u003e\n\u003cp data-end=\"1393\" data-start=\"1174\"\u003e\u003cstrong data-end=\"1199\" data-start=\"1174\"\u003eForsyth RK et al. (2006)\u003c\/strong\u003e – double-blind study: oral glucosamine HCl + chondroitin sulphate; gait\/movement parameters were assessed in a \"veteran horses\" setting.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-end=\"1591\" data-start=\"1394\"\u003e\n\u003cp data-end=\"1591\" data-start=\"1397\"\u003e\u003cstrong data-end=\"1417\" data-start=\"1397\"\u003ePearson W (2009)\u003c\/strong\u003e – review: a \"low quality of evidence\" type summary of glucosamine-based joint supplements for dogs (in vivo studies).\u003cbr\u003e\u003cbr\u003eDogs: \u003cmeta charset=\"utf-8\"\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1863\" data-end=\"2124\"\u003e\n\u003cp data-start=\"1866\" data-end=\"2124\"\u003e\u003cstrong data-start=\"1866\" data-end=\"1888\"\u003eKampa N et al. (2023)\u003c\/strong\u003e – prospective, randomised, double-blind, placebo-controlled clinical study; glucosamine HCl + chondroitin sulphate (hip OA setting) compared to placebo and other groups.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"2125\" data-end=\"2329\"\u003e\n\u003cp data-start=\"2128\" data-end=\"2329\"\u003e\u003cstrong data-start=\"2128\" data-end=\"2153\"\u003eMcCarthy G et al. (2007)\u003c\/strong\u003e – randomised, double-blind, positive-controlled study: glucosamine\/chondroitin vs. carprofen; symptom scores were assessed.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Chia de Gracia","offers":[{"title":"500 g","offer_id":56381311451462,"sku":"58","price":42.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0100\/2360\/0213\/files\/glukosamiini_ml_836dde16-b05b-4810-9ddb-597c62731c28_1.jpg?v=1776253583","url":"https:\/\/www.chiadegracia.com\/products\/glucosamine-for-dogs","provider":"Chia de Gracia EN","version":"1.0","type":"link"}